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Neuroscience of MDMA

MDMA promotes the release of serotonin, dopamine, and norepinephrine.

• Serotonin: Enhances mood, empathy, and emotional connection.
• Dopamine: Increases reward and motivation.
• Norepinephrine: Elevates energy and alertness.

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Duration and Effects

• Onset: 30–60 minutes after ingestion.
• Peak: 2–3 hours of intense euphoria and empathy.
• Duration: 4–6 hours total.
• After‑effects: Fatigue, mood dips, and serotonin depletion.

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Risks and Side Effects

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• Dehydration and overheating during prolonged activity.
• Serotonin syndrome with high doses.
• Neurotransmitter depletion, leading to comedowns.
• Unreliable purity in underground markets.

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Legal Status in Canada

• Recreational use: Illegal under Canadian law.
• Therapeutic research: Approved in limited clinical trials.
• Possession or sale: Punishable under the Controlled Drugs and Substances Act.

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At mushroomsworld.ca, our mission is to provide educational, science‑based resources about entactogens, their neuroscience, cultural context, and legal status. We encourage readers to seek knowledge, prioritize safety, and follow legal frameworks.